Albendazole

(al ben' da zole)

Brand Name(s): Albenza^®; also available generically

WHY is this medicine prescribed?

Albendazole is used to treat neurocysticercosis (infection caused by the pork tapeworm in the muscles, brain, and eyes that may cause seizures, brain swelling, and vision problems). Albendazole is also used along with surgery to treat cystic hydatid disease (infection caused by the dog tapeworm in the liver, lung, and lining of the abdomen that may damage these organs). Albendazole is in a class of medications called antihelmintics. It works by killing the worms.

Are there OTHER USES for this medicine?

Albendazole is also sometimes used to treat infections caused by roundworms, hookworms, threadworm, whipworm, pinworm, flukes, and other parasites (a plant or animal that lives within another living organism to receive some benefit). Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

HOW should this medicine be used?

Albendazole comes as a tablet to take by mouth. It is usually taken with food twice a day. When albendazole is used to treat neurocysticercosis, it is usually taken for 8 to 30 days. When albendazole is used to treat cystic hydatid disease, it is usually taken for 28 days, followed by a 14-day break, and repeated for a total of three cycles. Take albendazole at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take albendazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are giving the medication to a child or if you cannot swallow the tablets whole, you may crush or chew the tablets and swallow the medication with a drink of water.

Take albendazole until you finish the prescription, even if you feel better. If you stop taking albendazole too soon or skip doses, your infection may not be completely treated.

What SPECIAL PRECAUTIONS should I follow?

Before taking albendazole,

• tell your doctor and pharmacist if you are allergic to albendazole, mebendazole, any other medications, or any of the ingredients in albendazole tablets. Ask your pharmacist for a list of the ingredients.

• Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take while taking albendazole. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

• The following nonprescription product may interact with albendazole: cimetidine (Tagamet). Be sure to let your doctor and pharmacist know that you are taking these medications before you start taking albendazole. Do not start any of these medications while taking albendazole without discussing with your healthcare provider.

• tell your doctor if you have or have ever had liver disease.

• tell your doctor if you are pregnant, could be pregnant, or plan to become pregnant. You should not begin your treatment with albendazole until you have taken a pregnancy test with negative results. You should not become pregnant while you are taking albendazole and for 3 days after your final dose. Talk to your doctor about birth control methods that you can use during your treatment. If you become pregnant while taking albendazole, call your doctor immediately. Albendazole may harm the fetus.

• tell your doctor if you are breast-feeding.

• if you are taking albendazole to treat neurocysticercosis, your doctor will probably tell you to take certain medications to prevent damage to the nervous system during your treatment. Call your doctor right away if you have any of the following symptoms: seizures, headache, vomiting, extreme tiredness, or changes in behavior.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do IF I FORGET to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Albendazole may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• stomach pain
• nausea
• vomiting
• headache
• dizziness
• reversible hair loss

Some side effects can be serious. If you experience any of these symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately:

• sore throat, fever, chills, and other signs of infection
• unusual bleeding or bruising
• weakness
• fatigue
• pale skin
• shortness of breath
• rash
• hives

Albendazole may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What should I do in case of OVERDOSE?

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What OTHER INFORMATION should I know?

Keep all appointments with your doctor and the laboratory. Your doctor may order an eye exam before beginning your treatment. Your doctor will also order certain lab tests during your treatment to check your body's response to albendazole.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. represents that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS^® Patient Medication Information™. © Copyright, 2024. The American Society of Health-System Pharmacists^®, 4500 East-West Highway, Suite 900, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: October 15, 2023.